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TB-500 acts systemically, mobilizing stem cells, suppressing inflammatory cytokines, and regulating actin for tissue remodeling

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In order to investigate the intracellular molecular transformation and the morphology transformation of NSBSO which showed good GSH-response in vitro and excellent selective cellular toxicity, we conducted LCMS, confocal laser scanning microscopy (CLSM) and Bio-TEM analysis

Livers were cannulated through the inferior vena cava via the right atrium and perfused with a calcium- and magnesium-free HBSS containing 10 mM HEPES, 0.5 mM EGTA followed by perfusion with Williams E medium containing 50 mM HEPES and type IV collagenase

DOI:10.1016/j.csbj.2022.03.028 30