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These real-world findings provide insights into the effectiveness and tolerability of these medications outside the controlled environment of RCTs, reinforcing the potential of tirzepatide as a highly effective option for weight management in routine clinical practice

In addition to its structural advantage, MOTS-c interact with and regulate many different nuclear genome-encoded proteins such as mechanistic target of rapamycin complex 1 (mTORC1) and AMP-activated protein kinase (AMPK)

Patients should avoid lying down immediately after eating and stay well-hydrated with small, frequent sips of water or electrolyte solutions

Tirzepatide HypoSpray therapy may be considered only when clinically appropriate, and it requires medical provider oversight from review through prescription access

The biliary system carries bile, a digestive fluid produced in the liver and sent to the gallbladder and intestines