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Open communication with your healthcare provider about symptom timing and severity helps determine whether adjustments to your treatment approach are needed

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Obesity-related asthma typically manifests as a conglomerate of interconnected immuno-metabolic systems and may therefore benefit from shared therapeutic interventions, such as glucagon-like peptide-1 (GLP-1) agonism

For patients with severe renal insufficiency (CrCl less than 30 mL/min, approximately corresponding to serum creatinine levels of greater than 3.0 mg/dL in men and greater than 2.5 mg/dL in women) or with end-stage renal disease (ESRD) requiring hemodialysis or peritoneal dialysis, the dose of Januvia is 25 mg once daily