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have reported in healthy male smokers ( n = 21) compared to non-smokers ( n = 21) a significant increase in externalization of PS to the outer leaflet of the RBCs membrane, a hallmark of eryptosis, which was significantly correlated to the plasma level of CRP and GSH concentration in erythrocytes [440]

Tissue-specific expression analysis revealed significant enrichment of associated genes in metabolically active tissues, most prominently in the kidney cortex (P adj -value = 6.3010), with nominally significant enrichment in the gastrointestinal tract (transverse colon, P adj -value = 0.03)

Food supplement can not be used as a substitute (replacement) of a varied diet

Notably, a 24-week semaglutide trial reported improvements in sperm morphology and cholesterol levels while maintaining stable hormone levels

However, dietary habit represents a complex entity owing to the differences in dietary components such as macronutrients, micronutrients, salt, and food additives