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Getting the dose right is key to avoid giving too little or too much vitamin B12

Neuroscientific research has further examined the peptides interaction with monoaminergic pathways, particularly those involving dopamine and serotonin signaling

Adverse Reactions/Side Effects Generalized: Anaphylactic shock and death have been reported with administration of parenteral vitamin B 12(see WARNINGS)

When stratified by administration route, the mean percentage changes were: Intramuscular (IM): 307% Oral: 285% Sublingual: 199% IM administration showed the highest average B12 increase, although oral and sublingual routes also yielded substantial improvements, supporting their use as effective and less invasive alternatives

from Wagner College in 1959 and his M.S