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By analyzing the reported adverse events in the US Food and Drug Administrations database, Elashoff reported that treatment with DPP4 inhibitor sitagliptin or GLP-1R agonist exenatide increased the risk of pancreatitis and pancreatic cancer as compared with other therapies

That's just a business decision in the contract that the PBMs have made

[9] Use as a solvent [edit] Because of its polarity and thermal stability, molten DMSO 2 has been used industrially as a high-temperature solvent

While the LDL changes reversed during washout, the HDL increase did not