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Lactylation serves as the bridge between metabolism and epigenetics Lactate intensifies the crosstalk between metabolism and epigenetics 18,19,20,209,210 (Fig

Administration of exogenous carnitine as an adjunct to VPA therapy is thought to restore beta-oxidation to mitochondria cells of the liver, accept toxic acyl moieties from CoA, and relieve the inhibition of urea synthesis.[3] However, our findings suggested that the effective utilization of levocarnitine transport into mitochondria, which may be individually different, might play an important role to lead these favorable processes

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