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However, the group receiving both AOD9604 and HA showed the most favorable results, suggesting a potential synergistic interaction

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If your heart is already running at maximum capacity, Grayson said, it cant adequately ramp up to meet the increased demands of exercise or stress, but it will try, so over time, the drug can also cause cardiomyopathy, or an enlargement of the heart that makes it more difficult to pump blood properly and can eventually lead to heart failure