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A new hypothesis suggests that trigger points may occur due to a failure of protective regulatory mechanisms that prevent excessive muscle activity or that prevent a potentially injurious accumulation of [calcium ions] within muscle cells, according to a recent paper published in the International Journal of Molecular Science

[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Micheli V, Simmonds HA, Sestini S, and Ricci C

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