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However, their long term use may produce local side effects such as irritation and upper respiratory tract infections

Am J Physiol Renal Physiol (2007) 293(4):F106571

Hansoh Pharma will also receive royalties on the product's sales outside China

Kidney injury molecule 1 (KIM-1) is an immunoglobulin superfamily protein that is significantly upregulated in the injured proximal tubule, and the expression of KIM-1 is increased in the kidney, blood and urine of patients with DKD (33)

However, no single GLP-1 is definitively 'easiest' for everyone, and careful dose titration alongside dietary adjustments can significantly improve tolerability across all agents