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For all the included studies, study quality was assessed using the standard NICE checklist, which evaluates 7 domains relating to randomization, blinding, imbalances between treatment groups, outcomes measured and reported, and handling of missing data

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To account for attrition, a target sample size of 250 participants per group was set

Moreover, recent clinical studies and real-world clinical data have revealed broader pleiotropic effects of these drugs , opening doors for repurposing and extending the commercial lifespan of these drugs

Hsu GL, Chen HS, Hsieh CH et al: Long-term results of autologous venous grafts for penile morphological reconstruction