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MSD's head of R&D, Dean Li, said that the licensing deal will "build on our experience targeting incretin biology to evaluate HS-10535 and its potential to provide additional cardiometabolic benefits beyond weight reduction." The company has a history in the incretin (gastrointestinal hormone) space with Januvia (sitagliptin), which targets DPP-4 and is a blockbuster treatment for type 2 diabetes, although it is now approaching the end of its patent life in the US and already seeing generic competition in other markets

Gut barrier disruption and chronic disease