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Clinical and biochemical features of patients comprised in K1, K2, and K3 clusters

Table of Contents Understanding reduced response to GLP-1 therapy Causes and risk factors Identifying poor response early Adjusting treatment strategies Understanding Reduced Response to GLP-1 Therapy GLP-1 receptor agonists have transformed diabetes care by improving glycemic control and promoting weight loss

Genetic Variations and GLP-1 Receptor Sensitivity Recent pharmacogenetic research has identified genetic variants in the GLP1R gene (rs6923761) that may influence how individuals respond to GLP-1 receptor agonists

433 Birtles, L

Patients may also have a harder time losing weight if they are on certain medications at the same time as a GLP-1 that can promote weight gain, such as certain antidepressants and beta blockers, Glickman says