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doi: 10.1523/jneurosci.2868-05.2005 125 FialaMZhangLGanXSherryBTaubDGravesMCet al

Tissue-Specific Distribution : The enhanced bioavailability allows for preferential accumulation in glutathione-dependent organs, particularly the liver for detoxification processes and the lungs for respiratory support against oxidative stress

Lipoic acid has been found to activate the insulin signaling cascade in cultured cells (3, 42, 43), increase GLUT4 translocation to cell membranes, and increase glucose uptake in cultured adipose and muscle cells (44, 45)

Indeed, a mounting number of studies have demonstrated that RCD of erythrocytes can occur and that it is most frequently executed without recruitment of caspase-3 [19]

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