14-3-3 Zeta/delta(Phospho Thr232) Polyclonal Antibody, 50ul Polyclonal Antibodies GORASP2 encodes a member of

GORASP2 encodes a member of the Golgi reassembly stacking protein family

The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors

where it will preferentially insert guanosine

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Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue

14-3-3 Zeta/delta(Phospho Thr232) Polyclonal Antibody, 50ul Polyclonal Antibodies GORASP2 encodes a member ofThis gene product belongs to the 14 3 3 family of proteins which mediate signal transduction by binding to phosphoserine containing proteins. This highly conserved protein family is found in both plants and mammals and this protein is 99% identical to the mouse rat and sheep orthologs. The encoded protein interacts with IRS1 protein suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that