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In the present study, we investigated whether specific plasma metabolites were associated with recovery of euthyroidism in patients with GD using untargeted metabolomics analyzed by liquid chromatography (LC)-mass spectrometry (MS)

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The theory about the results here is that weight loss might affect brain cells involved in a particular hormonal signaling system (the hypothalamic-pituitary-testicular axis) that is impaired in men with metabolic hypogonadism, the researchers say

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