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Additionally, Chang et al (110) demonstrated that exenatide exerted cardioprotective effects against oxidative stress-induced injury both in vitro and in vivo, which was potentially attributed to the clearance of oxidative stress products (such as ROS), increased concentrations of antioxidant defense enzymes and suppression of myocardial cell apoptosis

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The Ala-Glu-Asp sequence appears to influence osteoblasts via mechanisms similar to those in chondrocytes, supporting mineralization

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